How Does X-trant Work

X-Trant (containing the active ingredient Estramustine phosphate) works by combining the effects of estrogen and a nitrogen mustard chemotherapy agent. Estramustine is a prodrug, meaning it is inactive until metabolized into its active form in the body.

Benefits Of X-trant

X-Trant (Estramustine phosphate) offers significant benefits, particularly in the treatment of prostate cancer, especially in cases that are advanced or resistant to other therapies. The medication works by combining chemotherapy and hormonal therapy in one treatment, which allows it to target cancer cells from multiple angles.

Often used as adjuvant therapy after tamoxifen or on its own.

The most common side effects of X-trant are
• Hot flashes
• Nausea or vomiting
• Diarrhea
• Loss of appetite
• Fatigue
• Swelling in the ankles or feet
• Headache
• Dizziness
• Breast tenderness or enlargement
• Skin rash

Other side effects of X-trant can include

• Severe heart problems (e.g., chest pain, irregular heartbeat)
• Blood clots (e.g., deep vein thrombosis, pulmonary embolism)
• Severe liver issues (e.g., jaundice, dark urine, upper abdominal pain)
• Severe gastrointestinal problems (e.g., blood in stool, black or tarry stools)
• Severe allergic reactions (e.g., rash, itching, swelling, or difficulty breathing)
• Vision changes (e.g., blurred vision, eye pain)
• Bone pain or fractures
• Severe mood changes or depression
• Swelling in the abdomen (sign of possible fluid retention or liver issues)
• Fatigue or weakness that is unusual or persistent

Who Should Not Take X-trant

X-Trant (Estramustine phosphate) should not be taken by individuals who are allergic to Estramustine or any of its components, as it can cause serious allergic reactions. It is also not recommended for women, as Estramustine is intended for use in men with prostate cancer, and its hormonal effects could cause harm to women. Individuals with severe liver disease should avoid X-Trant, as the medication is metabolized by the liver, and impaired liver function may lead to harmful accumulation of the drug in the body.

How To Take X-trant

X-Trant (Estramustine phosphate) should be taken exactly as prescribed by your healthcare provider. Typically, it is administered in the form of a capsule, usually taken once or twice a day. It is crucial to take X-Trant on an empty stomach, at least 1 hour before or 2 hours after eating to ensure the best absorption of the medication. The capsule should be swallowed whole with a full glass of water—do not chew, crush, or break the capsule.