How Does Trombopag 50mg Work

Trombopag 50 mg, which contains the active ingredient eltrombopag, works by stimulating the production of platelets in the bone marrow.
Eltrombopag is a thrombopoietin receptor agonist—it mimics the action of the natural hormone thrombopoietin (TPO). Thrombopoietin is responsible for regulating the production of platelets by binding to and activating TPO receptors (also called c-Mpl receptors) found on the surface of precursor cells in the bone marrow.

Benefits Of Trombopag 50mg

Trombopag 50 mg offers significant benefits for patients suffering from conditions that lead to low platelet counts, such as chronic immune thrombocytopenic purpura (ITP), hepatitis C-associated thrombocytopenia, and severe aplastic anemia (SAA). By stimulating the thrombopoietin receptors in the bone marrow, Trombopag increases the production of platelets, helping to reduce the risk of bleeding.

The most common side effects of Trombopag 50mg are
• Nausea
• Headache
• Fatigue (tiredness)
• Diarrhea
• Upper respiratory tract infection
• Muscle aches or pain (myalgia)
• Back pain
• Elevated liver enzymes (increased ALT, AST)
• Cough
• Loss of appetite

Other side effects of Trombopag 50mg can include
• Blood clots (thromboembolic events) – such as deep vein thrombosis or stroke
• Liver toxicity – including elevated bilirubin or liver failure in rare cases
• Cataracts – clouding of the lens in the eye, especially with long-term use
• Bone marrow fibrosis – scarring of the bone marrow, which can affect blood cell production
• Rash or skin reactions
• Abdominal pain
• Dry mouth
• Tingling or numbness (paresthesia)
• Dizziness
• Depression or mood changes

Who Should Not Take Trombopag 50mg

Trombopag 50 mg should not be taken by individuals who are allergic to eltrombopag or any of its inactive ingredients. It is also not recommended for patients with a history of severe liver disease unless the benefits clearly outweigh the risks, as the medication can increase liver enzyme levels and potentially cause liver toxicity. People with a high risk of blood clots, such as those with a history of thromboembolic events, may need to avoid Trombopag or use it with extreme caution, as it can increase the likelihood of clot formation when platelet counts rise too high.

How To Take Trombopag 50mg

Trombopag 50 mg should be taken exactly as prescribed by your healthcare provider. It is typically taken once daily, on an empty stomach, either 1 hour before or 2 hours after a meal to ensure proper absorption. It’s important to avoid taking the medication with dairy products, calcium, magnesium, iron, or zinc supplements, as these can interfere with how well your body absorbs the drug. Always swallow the tablet whole with a glass of water—do not crush or chew it.