Pomalid by Natco is a generic version of Pomalidomide, an oral immunomodulatory agent derived from thalidomide. It is primarily used for the treatment of relapsed and refractory multiple myeloma in adult patients who have received at least two prior therapies, including lenalidomide and a proteasome inhibitor, and have demonstrated disease progression.
Category | Immunomodulatory Agent |
Brand | Natco |
Ingredient | Pomalidomide |
Prescription Required | Yes |
Strength | 1,2, and 4 mg |
Package | 21 Tablets |
Pomalid 1 mg, 2 mg, and 4 mg (pomalidomide) work by modulating the immune system and targeting cancerous cells in multiple ways. As a derivative of thalidomide, pomalidomide belongs to a class of drugs called immunomodulatory agents. It enhances the body’s natural immune response by activating T-cells and natural killer (NK) cells, which are crucial in identifying and destroying cancer cells. Pomalidomide also inhibits the growth of new blood vessels (angiogenesis) that tumors need to survive and expand.
Lenalidomide (available in 5mg, 10mg, 15mg, and 25mg) offers several significant benefits for patients with certain types of cancer and blood disorders. One of the primary benefits is its ability to modulate the immune system, enhancing the body’s ability to fight cancer by stimulating T-cells and natural killer (NK) cells to attack abnormal or malignant cells.
The most common side effects of Pomalid 1,2 and 4 mg are
• Neutropenia (low white blood cell count)
• Anemia (low red blood cell count)
• Thrombocytopenia (low platelet count)
• Fatigue
• Dizziness
• Headache
• Insomnia
• Constipation
• Diarrhea
• Nausea
Other side effects of Pomalid 1,2 and 4 mg can include
• Blood clots (deep vein thrombosis, pulmonary embolism)
• Shortness of breath or chest pain (may indicate a clot or lung issue)
• Liver function abnormalities (elevated liver enzymes)
• Allergic reactions (swelling, itching, difficulty breathing)
• Peripheral neuropathy (numbness or tingling in hands or feet)
• Increased risk of secondary cancers (e.g., acute leukemia)
• High blood pressure
• Low blood pressure
• Mood changes or depression
• Confusion or mental status changes
Pomalid 1 mg, 2 mg, and 4 mg (pomalidomide) should not be taken by individuals who are pregnant or planning to become pregnant, as the drug is known to cause severe birth defects or fetal death. Women of childbearing potential must use effective contraception before, during, and after treatment, and pregnancy must be ruled out before starting therapy.
Pomalid 1 mg, 2 mg, and 4 mg (pomalidomide) should be taken exactly as prescribed by a healthcare professional, typically in 28-day treatment cycles. The most common schedule involves taking the capsule once daily on days 1 to 21 of each 28-day cycle, followed by a 7-day rest period with no medication. It is taken by mouth, usually at the same time each day, with or without food. The capsules must be swallowed whole with water—do not crush, chew, or open them
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