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Nuparp 300mg Tablet By Zydus Pharma

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Nuparp 300 mg Tablet, manufactured by Zydus Cadila, is an anticancer medication classified as a PARP (poly ADP-ribose polymerase) inhibitor. The active ingredient is Rucaparib, a synthetic drug designed to interfere with DNA repair mechanisms in cancer cells.

Nuparp 300mg by zydus Details

Category Anticancer medication
Brand Zydus
Ingredient Rucaparib
Prescription Required Yes
Strength 300mg
Package 10 Tablets
Category:

How Does Nuparp 300mg By Tablet Work:

Nuparp 300 mg (Rucaparib) works by inhibiting an enzyme called poly ADP-ribose polymerase (PARP), which plays a crucial role in repairing damaged DNA within cells. Cancer cells, especially those with BRCA mutations (common in ovarian, breast, and prostate cancers), rely on PARP to repair their DNA and continue growing. By blocking PARP, Nuparp prevents these cancer cells from fixing the DNA damage caused by chemotherapy or radiation, leading to an accumulation of DNA errors. As a result, the cancer cells are unable to survive and proliferate, ultimately causing them to die.

Benefits Of Nuparp 300mg

Nuparp 300 mg (Rucaparib) offers significant benefits, particularly for patients with ovarian cancer, prostate cancer, and other cancers associated with BRCA mutations. One of its key advantages is its ability to enhance the effectiveness of chemotherapy by preventing the repair of DNA damage in cancer cells. This is especially beneficial in cancers that rely on DNA repair mechanisms, as Nuparp targets these repair pathways, leading to cancer cell death and inhibiting tumor growth.

The most common side effects of Nuparp 300mg are:
• Nausea
• Fatigue
• Anemia (low red blood cell count)
• Loss of appetite
• Vomiting
• Diarrhea
• Headache
• Low platelet count (thrombocytopenia)
• Increased liver enzymes (indicating possible liver issues)
• Dizziness

Other side effects of Nuparp 300mg can include:
• • Bone marrow suppression (leading to low levels of red blood cells, white blood cells, and platelets, increasing the risk of infection, bleeding, or anemia)
• Liver toxicity (e.g., jaundice, dark urine, pain in the upper right abdomen)
• Pneumonitis (inflammation of the lungs, leading to difficulty breathing or cough)
• Renal impairment (kidney problems)
• Severe gastrointestinal issues (e.g., persistent diarrhea, dehydration)
• Chest pain
• Shortness of breath
• Severe fatigue or weakness
• Severe allergic reactions (e.g., rash, itching, swelling, difficulty breathing)
• Mental confusion or cognitive changes (in rare cases)

Who Should Not Take Nuparp 300mg

Nuparp 300 mg (Rucaparib) should not be taken by individuals who have a known allergy to Rucaparib or any of the other ingredients in the medication, as it may cause severe allergic reactions. It is also contraindicated for individuals with severe liver impairment, as the drug is metabolized in the liver, and impaired liver function can increase the risk of serious side effects.

How To Take Nuparp 300mg

Nuparp 300 mg (Rucaparib) should be taken exactly as prescribed by your healthcare provider, typically twice a day. It is important to swallow the tablet whole with a glass of water—do not crush, chew, or break the tablet, as this can affect how the medication works. Nuparp can be taken with or without food, but it is recommended to take it at the same times each day to help remember your dosing schedule.

 

 

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