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Hepcinat Plus Tablet By Natco Pharma

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Hepcinat Plus is a fixed-dose combination tablet developed by Natco Pharma Ltd for the treatment of chronic hepatitis C virus (HCV) infection. This formulation combines two antiviral agents—Sofosbuvir 400 mg and Daclatasvir 60 mg—into a single tablet, simplifying the treatment regimen for patients.

Hepcinat Plus Tablet by natco Pharma  Details:

Category Antiviral drug
Brand Natco
Ingredient Sofosbuvir
Prescription Required Yes
Strength 60/400mg
Package 28 Tablets
Categories: ,

How Does Hepcinat Plus Work:

Hepcinat Plus works by combining two antiviral agents, Sofosbuvir and Daclatasvir, to target different stages of the hepatitis C virus (HCV) lifecycle. Sofosbuvir is a nucleotide polymerase inhibitor that interferes with the viral RNA polymerase, an enzyme essential for the replication of the HCV genome. By blocking this enzyme, sofosbuvir prevents the virus from replicating and producing new viral particles.

Benefits of Hepcinat Plus:

Hepcinat Plus offers significant benefits in the treatment of chronic hepatitis C virus (HCV) infection. By combining two potent antiviral agents, Sofosbuvir and Daclatasvir, it provides a highly effective treatment option that targets different stages of the HCV lifecycle. Sofosbuvir inhibits the viral RNA polymerase, preventing the replication of the virus, while Daclatasvir disrupts the NS5A protein, which is essential for viral replication and assembly.

The most common side effects of Hepcinat Plus are:

  • Headache
  • Fatigue (tiredness)
  • Nausea
  • Diarrhea
  • Insomnia (trouble sleeping)
  • Loss of appetite
  • Dizziness
  • Irritability

Other side effects of Hepcinat Plus include:

  • Liver enzyme elevation (ALT, AST)
  • Hepatitis B reactivation (in co-infected patients)
  • Anemia (especially if combined with ribavirin)
  • Skin rash or itching
  • Depression or mood changes
  • Muscle or joint pain
  • Swelling of the face, hands, or feet
  • Chest pain or shortness of breath

Who Should Not Take Hepcinat Plus:

Hepcinat Plus should not be taken by individuals who are allergic to either of its active ingredients, sofosbuvir or daclatasvir, or to any of the tablet’s inactive components. It is also not suitable for people with severe liver impairment or decompensated liver disease unless specifically prescribed and closely monitored by a healthcare provider.

How To Take Hepcinat Plus:

Hepcinat Plus should be taken exactly as prescribed by a healthcare provider. The usual dose is one tablet taken once daily, containing Sofosbuvir 400 mg and Daclatasvir 60 mg, and it can be taken with or without food. It is important to take the medication at the same time each day to maintain consistent levels in the bloodstream.

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