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Geftinat Tablet By Natco Pharma

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Geftinat is a branded formulation of Gefitinib, developed and manufactured by Natco Pharma Ltd. It is primarily used in the treatment of non-small cell lung cancer (NSCLC), especially in patients with specific mutations in the EGFR gene. Gefitinib belongs to a class of drugs known as tyrosine kinase inhibitors (TKIs), which work by blocking signals that promote cancer cell growth and survival.

Geftinat By Natco Tablet

Category Anti Cancer Drugs
Brand Natco
Ingredient Gefitinib
Prescription Required Yes
Strength 250mg
Package 30 Tablets
Category:

How Does Geftinat 250mg Work

Geftinat 250mg, which contains the active ingredient Gefitinib, works by targeting a specific protein involved in the growth and survival of cancer cells. This protein, known as the epidermal growth factor receptor (EGFR), is often overactive in certain types of non-small cell lung cancer (NSCLC) due to genetic mutations. EGFR normally helps cells grow and divide, but when mutated, it can cause cells—particularly cancer cells—to multiply uncontrollably.

Benefits Of Geftinat 250mg

Geftinat 250mg offers several important benefits, particularly for patients with EGFR mutation-positive non-small cell lung cancer (NSCLC). One of its key advantages is that it is a targeted therapy, meaning it specifically inhibits the EGFR tyrosine kinase that drives the growth of certain cancer cells, making it more precise and often more effective than standard chemotherapy in selected patients. Because of this targeted action, Geftinat can lead to faster tumor shrinkage, delayed disease progression, and in some cases, improved overall survival.
Common Side Effects:

The most common side effects of Geftinat 250mg are
• Diarrhea
• Skin rash
• Acne or dry skin
• Nausea
• Vomiting
• Loss of appetite
• Fatigue (tiredness)
• Itching or skin irritation
• Mouth sores (stomatitis)
• Eye irritation (dry eyes, redness)
• Elevated liver enzymes (seen in blood tests)

Other side effects of Geftinat 250mg can include
• Interstitial lung disease (ILD)
• Severe liver damage or hepatitis
• Gastrointestinal bleeding or perforation
• Eye disorders (e.g., corneal ulceration, keratitis)
• Dehydration due to prolonged diarrhea or vomiting
• Severe skin reactions (blistering, peeling, or rash)
• Nail disorders (e.g., paronychia, brittle nails)
• Allergic reactions (swelling, hives, difficulty breathing)
• Increased susceptibility to infections
• Changes in kidney function (detected through blood tests)

Who Should Not Take Geftinat 250mg

Geftinat 250mg should not be taken by individuals who are allergic to Gefitinib or any of its inactive ingredients. It is also not recommended for patients who have a history of interstitial lung disease, as this medication can increase the risk of serious and potentially fatal lung complications. People with severely impaired liver or kidney function should avoid Geftinat unless specifically advised and closely monitored by a healthcare professional, since the drug is metabolized in the liver and excreted through the kidneys.

How To Take Geftinat 250mg

Geftinat 250mg should be taken exactly as prescribed by your healthcare provider. The usual recommended dose is one tablet (250 mg) taken orally once daily, with or without food. It should be swallowed whole with a glass of water—do not crush, split, or chew the tablet.

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